The 2025 college basketball season comes to a thrilling close tonight with the Florida-Houston matchup for the national title. It’s been a wild ride to get here, and now we’re down to one game to decide it all. If you’re looking for National Championship betting picks, you’re in the right place. Let’s talk about what matters: The Florida-Houston pick, the college basketball National Championship odds and the best bets to close out the season.
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National Championship Betting Picks: Florida-Houston
We’ve seen Florida and Houston battle through tough opponents to earn their spot in the college basketball National Championship. Florida punched its ticket with an impressive second half surge against Auburn. Despite a slow start, it showed poise, experience and elite shot-making down the stretch. Walter Clayton Jr. was once again the spark, and this team proved it have the kind of championship DNA you want on the big stage.
Houston, meanwhile, came through a rollercoaster of a game that tested its resilience. It has long been known for its defense, but this year’s squad adds something different: Shot-making. L.J. Cryer and Emanuel Sharp have transformed Houston into a legitimate offensive threat, and it made Duke pay for every defensive lapse in the semifinals.
This one’s tight. The spread is essentially a pick’em. You can find Florida -1 (-105) in most spots and Houston +1.5 if you’re willing to lay a little juice. Either way, you’re basically choosing a winner outright. And that’s exactly what we’re here to do.
This isn’t about bias or futures tickets — though there are some Florida ones in the mix — it’s about what we’ve seen from this Gators team all season long. Florida has shown an elite ability to adapt and handle adversity. From a loaded frontcourt to multiple guards who can defend and create, it has proven it can win in transition or in the half court. It’s physical, balanced and smart.
Yes, Houston has the firepower this year to hang with anyone, and it absolutely can win this game. But Florida’s length and depth are real problems for Houston. If it can disrupt Houston’s rhythm, rebound well and keep their own shooters in rhythm, it’s hard to imagine the Gators falling short.
The Gators have been a team to ride this tournament, and there’s no reason to jump ship now. They are built for this moment, and they have handled pressure at every stage. The matchup lines up well, and if they control the boards and guard the perimeter, they will finish what they started.
Best Florida-Houston College Basketball National Championship Pick: Florida -1 (-105, DraftKings)
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