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College Football PrizePicks Week 4 Predictions: Colorado Can’t Stop Bo Nix (September 23)

As the college football season enters Week 4, we eagerly anticipate another exciting Saturday. Highlighted by Colorado and Coach Prime taking on Oregon, we have a plethora of games to choose from, and finding the best college football PrizePicks plays can be a daunting task.

Fear not, as I’ve done the research and analysis to bring you my favorite and most promising picks for this Saturday’s slate of games. With the assistance of OddsShopper’s PrizePicks optimizer, these selections are designed to help you make informed choices and maximize your chances of success.

As a proven PrizePicks winner and seasoned content provider, you’ll always get three supporting data points to back up each play I recommend.

Let’s dive into my top PrizePicks predictions and turn your Saturday into a winning one. If you aren’t on PrizePicks yet, you can find the best PrizePicks promo code here.

College Football PrizePicks Week 4

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Bo Nix, Oregon – 342.5 Pass+Rush Yards

With all eyes on ColoradoOregon, let’s look at some plays to make your viewing more exciting and profitable. Colorado’s star quarterback Shedeur Sanders is getting all the attention, making Bo Nix overlooked in this matchup. The 70.5 game total is not only the highest for the Pac-12 but also the highest on the entire slate. The books are telling us Oregon is going to score a ton of points as they are 21.5-point favorites.

Let’s get into my three supporting stats.

Nix is averaging 317 pass + rush yards in three games. Two of those games were massive blowouts where he didn’t play in the fourth quarter. In Oregon’s eight-point victory at Texas Tech, Nix had a combined 405 pass + rush yards.

Oregon has the No. 1 rated OL pass-blocking efficiency in the country. Nix will have plenty of time in the pocket.

Colorado’s 460.3 yards allowed per game are ninth most in the FBS, and Nix has accounted for 56 percent of Oregon’s total yards, despite not playing a full game yet.

College Football PrizePicks Pick: MORE

Xavier Weaver, Colorado – 94.5 Receiving Yards

I like stacking high-total games for flex plays, and that’s exactly what we are doing here with Weaver. Again, this game total is 70.5, and given Colorado is a three-touchdown underdog, they will need to pass to keep up with the Ducks. This plays in our favor as the Buffaloes are a pass-first team, averaging only 2.0 yards-per-carry on 92 rushing attempts in three games. If they can make this competitive, it will be through the air.

Weaver leads the team with 32 targets and 386 yards. His 32 targets are tied for fourth in the country for players who’ve played three games.

Two-way star Travis Hunter had 23 targets before exiting early last week. He’ll miss this game, opening the door for more volume for Weaver.

Weaver’s 386 receiving yards rank fifth in the country, and even though it took overtime to record his 98 yards last week, his 128.7 yards per game are well over this prop.

Oregon allowed 282 passing yards to Texas Tech, which is a much more balanced team than Colorado.

College Football PrizePicks Pick: MORE

Cade McNamara, Iowa – 155.5 Passing Yards

No. 24 Iowa will visit Big Ten rival No. 7 Penn State in a battle of 3-0 teams. This game has a total of 39.5, which has come down from its opening of 41.5. The Hawkeyes are 14.5-point underdogs. These two teams are defense-first, both in the top-25 in yards allowed per game. This number seems low for a passing yards prop, but let me tell you why “LESS” is the play.

Cade McNamara has completed just 53 percent of his 71 pass attempts in three games, and Iowa has recorded 454 rushing yards compared to 452 passing yards. They are a run-first team.

Last week, he was just 9-for-19 for 103 yards with two interceptions in a game that Iowa WON 41-10.

Penn State ranks 20th in overall defensive rating, 12th in pass rush, and has allowed just 165 passing yards per game.

It’s only a matter of time before McNamara gets replaced behind center if Iowa plans to do anything this season.

College Football PrizePicks Pick: LESS

Taylen Green, Boise State – 215.5 Pass+Rush Yards

Although Boise State’s record is 1-2, they’ll head to Snapdragon Stadium as 6.5-point favorites against home team San Diego State (2-2). This game has a total of 46.5 points.

San Diego State has allowed the 17th-most total yards on the season in the FBS.

In all four of the Aztecs’ games, the opposing quarterback has gone well over this total, even though they have not allowed more than 36 points in a game.

Green is by no means a good quarterback, carrying a mere 53 percent completion rate, but he’s averaging 226.3 Pass+Rush Yards a game. PrizePicks is willing to give us 10 yards against a defense that ranks in the bottom 25 and 9th-worst against the run. I’ll take it.

College Football PrizePicks Pick: MORE

Two-pick power plays and five-pick flexes have the best EV on PrizePicks. If you’re looking for more advice on how to maximize your value, click here. 

Tim Speros

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Tim Speros

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