As the Thanksgiving festivities wind down and we all enter our annual food comas, the San Francisco 49ers and Seattle Seahawks will take center stage at Lumen Field. If you’re looking for some last-minute extra cash for Black Friday, consider tailing our picks! Let’s dive into the best 49ers-Seahawks player prop picks and anytime touchdown scorer bets for Thanksgiving, including a Deebo Samuel pick. Check out OddsShopper’s model and the rest of our NFL articles for the most up-to-date odds and additional picks!
49ers-Seahawks Player Props & Anytime Touchdown Bet | Thanksgiving
49ers-Seahawks Odds
Odds via FanDuel
49ers: -330 | Seahawks: +265
49ers -7: -115 | Seahawks +7: -105
Over 43.5: -115 | Under 43.5: -105
Time: Thursday, Nov. 23 at 8:10 p.m. ET
49ers-Seahawks Player Prop Pick
Deebo Samuel O/U 45.5 Receiving Yards
The do-it-all wide receiver for the San Francisco 49ers is back and ready to feast on Thanksgiving. Deebo Samuel has dealt with a plethora of injuries this season. His knee, ankle, and, recently, a shoulder injury kept him out of action. But if the last game was any indication of things to come, Samuel will have his way come Thursday, especially in the passing game. Samuel racked up 63 receiving yards on just three receptions in what proved to be an easy Week 11 win for the San Francisco 49ers. He now takes on the Seattle Seahawks as a seven-point favorite.
Last week against the Tampa Bay Buccaneers, Samuel saw 85% of the snaps — his most since Week 2. That tells me all I need to know about his health. Yes, he is on a short week, but playing 51 snaps last week means that he is ready to get unleashed here.
Thursday night is a perfect opportunity for Samuel to cash the over for his player prop receiving line. Teammate Brandon Aiyuk is coming off a career-high 156 yards and will ultimately get the tougher assignment, especially down the field. His 17 receptions of 20-plus yards is the sixth most in all of football. We’ll gladly settle for the Seahawks giving Samuel the short stuff to compensate for Aiyuk beating them down the field. Look for Samuel to cash this line for the sixth time in nine games this season.
49ers-Seahawks Player Prop Pick: Deebo Samuel Over 45.5 Receiving Yards -114 at FanDuel
49ers-Seahawks Anytime Touchdown Scorer
Let’s take a shot here with an offense loaded with weapons from top to bottom. The San Francisco 49ers have the best running back in all of football, an excellent wide receiver room, and one of the best tight ends in the league. That’s all led by formerly undrafted quarterback Brock Purdy.
Purdy finds himself within distance of the highly coveted MVP Award. According to FanDuel, Purdy has the sixth-best odds to win the award. Speaking of FanDuel, they’re also offering the best odds for Purdy to run a touchdown in at +650 on Thursday. That’s a price I’m willing to sprinkle on.
Most expect the 49ers to be living in the red zone come Thursday. What’s stopping Purdy from sneaking one in or taking one in for himself on a bootleg or a broken pocket? The rest of the major market has Purdy settled at +500, so buy this off-market number at FanDuel.
49ers-Seahawks Anytime Touchdown Scorer Bet: Brock Purdy +650 at FanDuel
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