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Cowboys-Chargers Pick & Prediction: Best Bet for Monday Night Football (Oct. 16)

The Dallas Cowboys and Los Angeles Chargers will do battle on Monday Night Football this week. The matchup sees former Cowboys offensive coordinator Kellen Moore take on his former employers — he now occupies the same role for the Los Angeles Chargers. Let’s dig into Monday’s Cowboys-Chargers betting odds as we make our predictions and pick the best NFL Week 6 bet! For the most updated Cowboys-Chargers odds, make sure to check out OddsShopper’s tools!

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Cowboys-Chargers Pick & Betting Prediction | Monday Night Football

Monday Night Football Odds

Odds via Bet365
Cowboys: -130 | Chargers: +110
Cowboys -1.5: -110 | Chargers +1.5: -110
Over 51: -110 | Under 51: -110
Expert: Isaiah Sirois
Time: Monday, Oct. 16 at 8:15 p.m. ET

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Cowboys-Chargers Pick & Prediction

The Dallas Cowboys just got embarrassed on national television this Sunday. In a matchup that some billed as an NFC Championship preview, the Cowboys managed only 10 points, three of which were scored after quarterback Dak Prescott was benched for the evening. Prescott had thrown three interceptions before getting relieved by Cooper Rush. The Cowboys will play another game out in California, this one against the Los Angeles Chargers. Former Dallas offensive coordinator (and quarterback) Kellen Moore leads the Chargers’ offense, and for as much confidence I have in him as a play-caller, the Chargers lack the personnel necessary to take care of business against the visiting team.

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Prescott goes from facing a top-six pass defense in expected points added (EPA) allowed per dropback to a bottom-six unit in the metric. The Chargers’ defense is so bad that the team’s big-name signing before the 2022 season, cornerback J.C. Jackson, had to get shipped back to the New England Patriots. The Chargers are coming off their bye for this matchup, but I’m not all that worried in this case — an off week won’t help a defense that ranks 26th in EPA allowed per dropback and 16th in EPA allowed per rush. The offense may get a shot in the arm with the return of running back Austin Ekeler, but both he and quarterback Justin Herbert will have a tough time beating a brutal Dallas defense.

Dallas’ defense comes into Week 6 ranked highly in most EPA metrics despite last weekend’s blowout loss. The Cowboys rank ninth in EPA allowed per rush and fourth in EPA allowed per dropback. They also rank first in pass-rush win rate (60%). The Chargers’ offensive line ranks a dreadful 26th in pass-block win rate (50%), so it’s unlikely that Herbert will have much time to through. Worse, Dallas’ defenders will be well-versed in Moore’s scheme. While that does cut both ways — the L.A. offense will be well-versed in what Dallas’ defense will do — the Chargers just don’t have the personnel or talent to stop Micah Parsons.

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I’m siding with Dallas to get a much-needed bounce-back win against Los Angeles on Monday Night Football. I’m generally skeptical of the Cowboys, but this is a must-win spot after Week 5’s embarrassing defeat. Dallas is an impressive 14-6 after a loss dating back to Mike McCarthy’s arrival in 2020. They are also a steady 10-5 as a road favorite with an average margin of 9.9, which is +4.2 relative to the spread. The Chargers are just 1-2 as a home underdog under Brandon Staley, and they are only 2-4 with a rest advantage. While I would love to see Moore score some revenge against his former employer on Monday night, the odds of that are far worse than the market suggests.

Cowboys-Chargers NFL Week 6 Pick: Dallas ML -122 at DraftKings

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Isaiah Sirois

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Isaiah Sirois

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