Happy Thanksgiving and welcome to our NFL PrizePicks predictions for Week 12, turkey edition. We have three games on the Thanksgiving slate kicking-off with the Packers at Lions, with the Commanders at Cowboys stuffed in the middle, and the 49ers at Seahawks to end the day. Let’s discuss the best PrizePicks plays for NFL Week 12, Thanksgiving day, starting with Christian McCaffrey.
With the assistance of OddsShopper’s PrizePicks optimizer, I’ve designed these plays to help you make informed choices and maximize your chances of success. If you aren’t on PrizePicks yet, you can find the best PrizePicks promo code here.
NFL PrizePicks Predictions for Week 12
Christian McCaffrey, 49ers, More/Less Than 0.5 Rush + Rec Yards
The 49ers will travel to Seattle as 7-point favorites over the division rival Seahawks. Christian McCaffrey needs just one yard from scrimmage and we win! That’s it. Do you really need to know that he leads the NFL in rushing yards and averages 38 receiving yards per game? Lock in this free square. You can wager up to $25 on PrizePicks promos like this one so make it count. I like to split these promos by entering a $20 power play and a $5 6-man flex play, but using all $25 on a power play also works!
NFL PrizePicks Play: Christian McCaffrey More Than 0.5 Rush + Rec Yards
CeeDee Lamb, Cowboys, More/Less Than 19 Fantasy Score
The Cowboys have a 30.25 implied team total and are 12-point home favorites over NFC East rival the Washington Commanders. CeeDee Lamb has a very favorable matchup in this one as Washington allows the third most fantasy points to wide receivers. He ranks ninth in targets and has the second most receiving yards with 1,013. He also has the third highest contested catch rate in the NFL, per PFF.
Lamb had 16.5 fantasy points last week with just 38 receiving yards. Washington is the worst defense in the NFL allowing 27.7 points per game. They allow the third most passing yards and 10th most rushing yards. Dallas may score through the air and on the ground, but Lamb will get his turkey leg today.
NFL PrizePicks Play: CeeDee Lamb More Than 19 Fantasy Score
Tyler Lockett, Seahawks, More/Less Than 4.5 Receptions
If Vegas is correct, the Seahawks will be playing from behind and will need to throw the ball. The 49ers have a stout defense allowing just 302.4 total yards and a league best 15.7 points per game. However, their defense funnels to short passes resulting in 155 receptions allowed to wide receivers, third most in the NFL.
Tyler Lockett finds himself is a good spot for this game script. He has 34 targets over his last five games and has had five or more targets in 9 of 10 games this season. He leads the team in targets, receptions, and touchdowns with five. Utilizing OddsShopper’s Positive EV Bets tool, we see that more than 4.5 receptions has a 2% EV rating and a 56% Win%. All other operators are heavy on the more side. Lockett gets to five receptions but hopefully I don’t eat five servings.
NFL PrizePicks Play: Tyler Lockett More Than 4.5 Receptions
Two-pick power plays and five-pick flexes have the best EV on PrizePicks. If you’re looking for more advice on how to maximize your value, click here.
