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NFL Week 2 Key Insights, Injuries, Bets & More

As Week 2 of the NFL season approaches, there are some key insights, injury reports, and betting odds that will influence the outcomes of matchups. In this information-driven post, we’ll focus on NFL Week 2 key insights, injuries, bets and more.

Nonetheless, here’s a breakdown of a few of the most important games, with a focus on key trends and best betting values.

Las Vegas Raiders at Baltimore Ravens (-9.5)

NFL Week 2 Key Insights:

  • Rest Advantage: The Ravens have a full 10 days of rest, providing a significant edge over the Raiders, who are traveling east.
  • Raiders’ Offensive Struggles: Las Vegas has the lowest implied total of the week at 16.5 points. Their offensive performance is concerning, with the 6th worst offensive DVOA from 2023.
  • Ravens’ Defense: Baltimore’s defense was ranked #1 in DVOA last season, setting them up well against a struggling Raiders offense.
  • Run Game: The Raiders had PFF’s 5th worst run defense last season, meaning we could see a big game from Baltimore’s rushing attack, including a likely heavy dose of Derrick Henry.

NFL Week 2 Key Injury:

  • Kyle Van Noy (Questionable)

NFL Week 2 Best Bet:

  • Ravens -8 at Circa: You can grab value with Ravens -8 at Circa (-110) or -8.5 at Caesars. With 85% of the bets backing the Ravens, this line might keep moving.

Tampa Bay Buccaneers at Detroit Lions (-7)

NFL Week 2 Key Insights:

  • Lions’ Strong Offense: Detroit has the highest implied point total on the slate. The line has already shifted from -5.5 to -7, with potential further movement due to injury news.
  • Bucs’ Defensive Woes: Tampa Bay’s secondary, already weak after allowing the second-most passing yards in the NFL last season, is further hampered by injuries.
  • Pressure Factor: Detroit generated PFF’s top pass rush grade in Week 1, which could spell trouble for a Bucs team missing defensive line starters.

NFL Week 2 Key Injuries:

  • Bucs: Antoine Winfield, Tykee Smith, Calijah Kancey, and Josh Hayes are out, weakening the defense further.
  • Lions: Lenei Sewell (ankle) is a DNP, which would be a massive loss for the Lions.

NFL Week 2 Best Bet:

  • Lions -6 at ESPNBet: While most books have Detroit at -7.5, you can still find -6 on ESPNBet at -135.

San Francisco 49ers at Minnesota Vikings (+6)

NFL Week 2 Key Insights:

  • Short Rest for 49ers: San Francisco is coming off a short week and will have to travel. While Christian McCaffrey is questionable, his status hasn’t moved the line significantly.
  • EPA Data: Week 1 Expected Points Added (EPA) data slightly favors the Vikings, making the +6 line tempting.
  • Strong Performances: Both the 49ers and Vikings were top-3 in PFF’s overall team grades after Week 1, highlighting this as a potentially close matchup.

NFL Week 2 Key Injuries:

  • Vikings WR Jordan Addison: Likely out due to injury.
  • Christian McCaffrey (Questionable)

NFL Week 2 Best Bet:

  • Vikings +6.5 on ESPNBet: With most other books offering +5, there’s good value in grabbing the +6.5 line on ESPNBet.

New Orleans Saints at Dallas Cowboys (-6)

NFL Week 2 Key Insights:

  • Line Movement: Opened at -7 but now sits at 6.5.
  • Saints Offensive Revolution: New OC Klint Kubiak has the Saints looking sharp, incorporating pre-snap motion on 85% of plays in Week 1.
  • Cowboys Defense: Dallas will likely be without starting TE Jake Ferguson, weakening their offensive attack.

NFL Week 2 Key Injuries:

  • Jake Ferguson (Questionable)
  • Marshon Lattimore (DNP)

NFL Week 2 Best Bet:


New York Jets @ Tennessee Titans (+3.5)

NFL Week 2 Key Insights:

  • Road Fatigue: The Jets are playing back-to-back road games on a short week, and the line has already shifted from +5 to +3.5.
  • Titans Concerns: DeAndre Hopkins saw limited snaps in Week 1, raising concerns about Tennessee’s offensive potential.

NFL Week 2 Key Injuries:

  • Jets DE Javon Kinlaw: Limited participant in Thursday practice.

NFL Week 2 Best Bet:

  • Jets -3.5 (-110 on Caesars): This game offers limited betting value, but the Jets at -3.5 is the safest play.

Cincinnati Bengals at Kansas City Chiefs (-6)

NFL Week 2 Key Insights:

  • Chiefs’ Rest Advantage: Like the Ravens, Kansas City has 10 days of rest heading into Week 2, which could prove crucial.
  • EPA Favors Chiefs: Expected Points Added data from Week 1 heavily leans toward the Chiefs.
  • Bengals’ Vulnerability: Cincinnati allowed the second-most receiving yards to tight ends in 2023, which could open up opportunities for the Chiefs’ passing game.

NFL Week 2 Key Injuries:

  • Tee Higgins (Questionable)
  • Ja’Marr Chase (Questionable)

NFL Week 2 Best Bet:

  • Chiefs -5 on Fliff: Best odds for Kansas City at -5, though other books have it at -5.5 or -6.

For more NFL Week 2 expert picks, check out our latest YouTube video on what’s the best plays!

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